At carnivores in Ryazan region Opisthorchis felineus has been revealed. Trematodes are diagnosed in a liver of an ordinary fox (Vulpеs vulpеs) at mixed infection. Carnivorous are infected at 6,25 %. It is the first case of opisthorchosis in the region.

In Stavropol the main carrier and the tank of a virus Crimean-kongo haemorragical fevers is tick Hyalomma marginatum. Disease of people carries natural focal character. The knowledge epizootology and morphobiological features of carrier ККGL will allow veterinary and medical experts to predict and prevent infection of people with a dangerous virus.

Helminth fauna of cattle in Vologda region is investigated. It is revealed 36 species of helminths, including 5 species of Trematoda, 7 – Cestoda and 24 Nematoda. Fasciola hepatica, Paramphistomum cervi, Moniezia benedeni, Cooperia oncophora, Oesophagostomum venulosum, Ostertagia ostertagi, O. circumcincta, Nematodirus helvetianus, Trichostrongylus axei, Haemonchus contortus, Strongyloides papillosus, Dictyocaulus viviparus, Trichocephalus skrjabini, T. ovis, Neoascaris vitulorum are the most distributed. 16 species of helminths, including Dicrocoelium lanceatum, P. ichikawai, Liorchis scotiae, M. expansa, Thysaniezia giardi, Taenia hydatigena larvae, Bunostomum trigonocephalum, Oe. columbianum, O. trifurcata, O. circumcincta, N. spathiger, T. axei, S. papillosus, Thelazia rhodezi, T. skrjabini, T. ovis and N. vitulorum were found in Vologda region for the first time.

The data on a current status of fish fauna in facilities are given. It is revealed 40 species of parasites in fishes. Prevalence of Monogenea is established. The carp is the most infected (19 species).

Season dynamics of Oribatidae in the pastures and their infection by Moniezia spp. larva are investigated. The opportunity and expediency of realization of helminthological estimations of pastures at monieziosis and others anoplocephalatosis is established.

The data on specific structure of trematodes in mollusks from genius Bithynia are done. It is revealed, that 33 species of trematodes 19 genius of 12 families from Bithynia Palaearctic have 12 versions of trixenic life cycles.

In Chechen Republic the helminthological estimation of pastures concerning Protostrongylus spp. of sheep are made. Infections of lambs register since June–July. Young growth and adults’ sheep are infected by Protostrongylidae within all the year.

Parasitic diseases cause a serious pathology. Sharp current with clinical displays mark at malaria, trichinellosis, amebiasis, leishmaniosis. Feature of the majority of parasitic diseases is their chronic current connected with long, sometimes long-term, parasiting of the agent in people that depends on life expectancy of the parasite and reinfection.

The review of works of research establishments of Russia is given in veterinary parasitology 2012. Distribution of parasitosis of cattle, sheep, raindeers, horses, pigs, carnivorous and fishes in territory of Russia, Byelorussia, Ukraine, Kazakhstan and Tadjikistan is investigated. The basic sources and factors of transfer of activators parasitic zoonosis are determined. Researches are carried out in the field of development of new generation of ecologically safe, modern means of preventive maintenance and immunodiagnostics of parasitic diseases. The new complex parasiticides are created and tested and their pharmacotoxicological properties investigated.

It is established dictyocaulosis, protostrongylosis, muelleriosis, cystocaulosis, ostertagyosis, trichostrongylosis, nematodirosis, haemonchosis, fasciolosis, cysticercosis and echinococcosis (larva) in sheep in Moscow region. Efficiency of ELISA in diagnostics of helminthosis of sheep has made 75,5–100 %. The most essential deviations in chemical compound of sheep’s meat are marked at pulmonary nematodosis, echinococcosis and fasciolosis.

The comparative analysis of biochemical parameters at thick-billed murre (Uria lomvia) and common murre (U. aalge) infected by cestodes Alcataenia armillaris (Cestoda: Dilepididae) and noninfected was carried out. Negative impact of tape-worms A. armillaris on a metabolism in an organism of thick-billed and common murres was shown. It was established that concentrations of total lipids, triglycerides and glucose in plasma of blood were decreased. Also activity of the lactatdegidrigenase was increased in plasma of blood of infected birds.

Urine dehydration structurization at experimental trichinellosis of rats is studied. In 4 weeks after exposure rats urine was analyzed with biocrystallomics methods. It was stated, that urine crystallogenic properties changes according to intensity of infection.

Toxascaris leonina causes a dystrophy of deciduacytes, villus necrosis, deterioration of blood circulation between mother and an embryo and immunopathological alteration in placenta. A chronic insufficiency in placenta develops. Normal development of puppies is broken. Puppies are born underdeveloped and with the lowered viability.

The mechanism of transamination enzymes, urea, antioxidant protection in blood and liver of cattle afflicted with fascioliasis is studied. It was found that in the liver of infected animals, the most intensive formation of glutamic acid transamination occurs at aspartic acid and asparagine in α-ketoglutarate. Also, these animals have higher blood levels of urea, a higher activity of AST, ALT and catalase and the content of ceruloplasmin and peroxidase activity of SOD decreased.

The new approach to gathering трихостронгилид ruminant, providing reception of washout of a free forage from particles and other impurity is developed.

Persistent effect of aversect combi against microfilaria Onchocerca spp. and Setaria spp. is studied. The drug in therapeutic dose of 0,2 mg/kg showed persistence effect during 4–6 months.

Simultaneous usage of microbiological, ecological and crystalloscopic methods can be used for estimation of disinfectants antibacterial and toxic activity. Disinfection action of the substance was made on the model of helminths eggs and pathogenic microorganisms (Staphylococcus aureus, Enterobacter aerogenes, Bacillus anthracis). Toxicity in vivo was estimated on mice urine.

The action of disinfectant dezavid on Toxocara canis eggs in vivo is investigated. Dezavid in concentration of 0,1 %, 0,2; 0,4; 0,8; 1,6; 2,4 and 3,2 % has oocid and larvicid actions. With increase of concentration of dezavid solutions the terms of larvae life in eggs T. сanis and the period of destruction of eggs are shortened. Dezavid is recommended for disinfection an environment and excrements of dogs from eggs T. сanis. It is expedient to use of dezavid in higher concentration for reduction of terms desinfection of environment.

In experiments on 20 cattle is studied the influence of vigisox at therapeutic (50 mg/kg), 3 male (150 mg/kg) and 5 male (250 mg/kg) increased doses on clinical, hematological and biochemical indices. Vigisox didn’t negative influence on the body of cattle. Chemotherapeutical index of vigisox is 5. The preparation is safe mean for therapy of the main helminthosis of cattle.

Acute toxicity of nadinat – new wide spectrum anthelmintic as a powder is investigated. It is established LD50 for rats and mice – 5000,7 and 2348 mg/kg respectively.

The results of scientific researches in veterinary parasitology are given.