Improving the Efficiency of Deworming Kittens and Puppies Using the Drug Gamavit
https://doi.org/10.31016/1998-8435-2018-12-4-90-93
Abstract
The purpose of the research is to evaluate therapeutic efficiency of Gamavit in the cases of dehelminthization of puppies and kittens.
Materials and methods. Researches were conducted on 18 puppies and 20 kittens of different breeds at the age from 3 weeks to 3 months which had been divided based on analogues into two groups on each animal type. Precautionary dehelminthization was conducted for one part of animals, forced dehelminthization for the other part of animals (presence of helminths' ootids in fecal masses Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum). Anthelmintic Dirofen-suspension was administered to animals of the first group orally as prescribed by instructions. Gamavit at a dose of 0.2 ml/kg was additionally administered as a single dose subdermally during dehelminthization of kittens and puppies of the second group.
Results and discussion. Vomiting, decreased appetite were noted in animals of control group (without administration of Gamavit) after dehelminthization. Visible adverse changes were not noted in animals of experimental group (with administration of Gamavit). Weakening of leukocytosis and lowering of ERS, increase in red blood cells and hematocrit level, descreased activity of transferring enzymes and LDH level were noticed in animals of this group suggestive of weakening of intoxication and inflammatory reaction. In contrast, increased activity of transferring enzymes and LDH level were noticed in animals of control group which allows to infer about persisting inflammatory events. Consequently, high therapeutic efficiency of Gamavit in the cases of precautionary and forced dehelminthization were elucidated.
About the Authors
V. V. AnnikovRussian Federation
Vyacheslav V. Annikov
335 Sokolovaya Street, Saratov, 410005
A. V. Krasnikov
Russian Federation
Alexandr V. Krasnikov
335 Sokolovaya Street, Saratov, 410005
E. S. Platitsyna
Russian Federation
Elizaveta S. Platitsyna
335 Sokolovaya Street, Saratov, 410005
References
1. Annikov V. V., Shcherbakova Yu. V. Infectious diseases of dogs and cats. Saratov. Express distribution. 2015: 110. (In Russ.)
2. Georgiu H., Belimenko V. V. Up-to-date methods of diacrisis and therapeutics of babesial disease in dogs. Rossiyskiy veterinarny zhurnal = Russian Journal of Veterinary Science. 2015; 2: 35–37. (In Russ.)
3. Grigoreva E. A., Pronin A. V., Sanin A. V., Narovlyanskiy A. N., Kozhevnikova T. N., Timofeeva T. Yu., Sanina V. Yu., Stepanova T. N., Gerasimova E. V., Ivanova A. M. Exposure of the medication Gamavit on the activity of natural killer cells. Veterinariya Kubani = Veterinary science of Kuban. 2016; 4: 27–28. (In Russ.
4. Grishina E. A., Erovichevnikov A. A. Biochemical justification of administration of combined therapy in acute phase of experimental animals’ helminthiasis. Zhurnal infektologii = Journal of infectology. 2017; 9(3): 32–39. (In Russ.)
5. Liberman E. L., Georgiu H., Belimenko V. V. Experience of administration of Gamavit in treatment blood protozoan disease of reindeer. Rossiyskiy veterinarny zhurnal. SHZH = Russian Journal of Veterinary Science. Live-stock animals. 2014; 4: 31–33. (In Russ.)
6. Pereslegina I. O., Dubrovina T. S., Zotova S. N. Clinical event of dog intoxication by anticoagulative rodenticide. Veterinariya i kormlenie = Veterinary Science and hand feeding. 2018; 5: 36–38. (In Russ.)
7. Pereslegina I. O., Dubrovina T. S., Klintsova T. Yu., Agafonova N. D., Zotova S. N. Gamavit and Рhоsрrenyl improve the efficiency of therapy of acute cats intoxication by ethylene glycol: 3 clinical events. Veterinariya i kormlenie = Veterinary Science and hand feeding. 2018; 3: 38–42. (In Russ.)
8. Sanin A. V., Sosnovskaya O. Yu., Sanina V. Yu., Kozhevnikova T. N., Vasilev I. K., Narovlyanskiy A. N., Pronin A. V. Details of immunomodulators administration in the cases of parasitic diseases. Veterinariya Kubani = Veterinary science of Kuban. 2010; 2: 15–18. (In Russ.)
9. Sanin A. V., Vasilev I. K. Problem of lowering toxity of antiprotozoal medications in the cases of babesial disease in dogs. Rossiyskiy veterinarny zhurnal = Russian Journal of Veterinary Science. 2007; 2: 43–45. (In Russ.)
10. Sanin A. V. Choice of anthelminthics and base of dehelminthization. Veterinarnaya klinika = Veterinarian clinic. 2003; 12: 18–20. (In Russ.)
11. Sanin A. V., Ozherelkov S. V., Zvartsev R. V., Pronin A. V., Narovlyanskiy A. N. Lowering of acute toxity of medication Imidosan under the action of Gamavit – possible prospects in the cases of treatment babesial disease in dogs. Rossiyskiy veterinarny zhurnal. MDZH = Russian Journal of Veterinary Science. 2009; 4: 56–60. (In Russ.)
12. Sanin A. V., Manko V. M. Nonspecific immunity. Gematologiya i transfuziologiya = Hematocytology and transfusiology. 1990; 7: 30–34. (In Russ.)
Review
For citations:
Annikov V.V., Krasnikov A.V., Platitsyna E.S. Improving the Efficiency of Deworming Kittens and Puppies Using the Drug Gamavit. Russian Journal of Parasitology. 2018;12(4):90-93. (In Russ.) https://doi.org/10.31016/1998-8435-2018-12-4-90-93