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THE STUDY OF THE TOLERABILITY OF THE DRUG "INSPECTOR KVADRO TUBS"

https://doi.org/10.31016/1998-8435-2019-13-2-50-57

Abstract

The purpose of the research is to study the tolerability of the complex drug for veterinary use “Inspector Kvadro Tabs” on animals in increased doses.

Materials and methods. Studies were conducted in veterinary clinics in Moscow (LLC "LEBEN" and LLC "Vet Cat") and based on FSBSI "VNIIGIS named after K. I. Skryabin. To study the effect of the drug on the animals' organism, 3 groups of 5 clinically healthy outbred animals were formed: cats of 1–2 years old weighing 3–6 kg, kittens of 7–12 weeks old weighing 600–1100 g, dogs of 1–3 years old weighing 8–11 kg, puppies 7–11 weeks old weighing 1–6 kg. The drug was used in 2- and 5-times increased doses three times with an interval of 7 days. During the experiment, the animals were monitored daily, noting their general condition, behavior, appetite, controlled their weight, and body temperature.

Results and discussion. It is established that "Inspector Quadro Tabs" in 2 and 5 times increased doses has a good tolerability of animals, does not adversely affect the general condition and behavior of cats, kittens, dogs and puppies. In the process of the experiment, no deviations of hematological, biochemical and urological parameters were noted.

About the Authors

I. A. Stepanova
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants – a branch of Federal State Budgetary Institution of Science "Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary Medicine named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences"
Russian Federation

28, B. Cheremushkinskaya street, Moscow, Russia, 117218.



E. A. Koshkarev
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants – a branch of Federal State Budgetary Institution of Science "Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary Medicine named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences"
Russian Federation
28, B. Cheremushkinskaya street, Moscow, Russia, 117218.


G. B. Arisova
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants – a branch of Federal State Budgetary Institution of Science "Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary Medicine named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences"
Russian Federation
28, B. Cheremushkinskaya street, Moscow, Russia, 117218.


References

1. Arisov M. V., Danilevskaya N. V., Kataeva T. S. “RolfClub 3D” drops, spray, collars – effective drugs against ectoparasites of dogs and cats. Mater. 4th Intern. vet. dermatol. simptoms. VetPharma scientific journal. St. Petersburg, 2015; 2(24): 38–44. (In Russ.)

2. Arisov M. V., Indyukhova Y. N. Clinical study of the insecticide acaricidal activity “RolfClub 3D collar for dogs”. Veterinariya, zootekhniya i biotekhnologiya = Veterinary, zootechny and biotechnology. M., 2014; 8: 56–59. (In Russ.)

3. Arisov M. V., Smirnova E. S., Arisova G. B., Stepanov V. A., Poselov D. S. Study of the tolerability and effectiveness of the new complex drug Gelmintal tablets based on moxidectin and praziquantel. Rossiyskiy parazitologicheskiy zhurnal = Russian journal of parasitology. 2016; 3: 403–408. (In Russ.)

4. Indyukhova E. N., Arisov M. V., Arisova G. B., Stepanova I. A. Toxicological Assessment of the Neoterica Protecto 12 Complex Insecticide Acaricidal Preparation. Rossiyskiy parazitologicheskiy zhurnal = Russian journal of parasitology. 2018; 12(3): 60–61. (In Russ.)


Review

For citations:


Stepanova I.A., Koshkarev E.A., Arisova G.B. THE STUDY OF THE TOLERABILITY OF THE DRUG "INSPECTOR KVADRO TUBS". Russian Journal of Parasitology. 2019;13(2):50-57. (In Russ.) https://doi.org/10.31016/1998-8435-2019-13-2-50-57

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ISSN 1998-8435 (Print)
ISSN 2541-7843 (Online)