Toxicological and therapeutic assessment of «Сoсtsidon suspension 5 %» at coccidiosis in pigs
Abstract
Parameters of acute toxicity of «Сoсtsidon Suspension 5 %» are studied at in- jection: LD50 for mice made 23750±938,7 mg/kg, for rats - 28541,7±1666,1 mg/kg that gives the reason to assign this medicine to the 4th class of toxicity - low- dangerous drugs. Total dose of «Сoсtsidon Suspension 5 %» applied in the begin- ning of effect exceeded many times over the value of single dose LD50. In this con- nection, the cumulatively coefficient is much more than 1 that pointed at the lack of cumulative properties of a medicine. Efficiency of «Сoсtsidon Suspension 5 %» by coccidiosis in pigs made 100 %. At injection of medicine and within the next 30 days side-effects and complications are not detected
About the Authors
D. S. Poselov
All-Russian Scientific Research Institute of Helminthology named after
K.I. Skryabin
Russian Federation
рostgraduate
Russian Federation
рostgraduate
M. V. Arisov
All-Russian Scientific Research Institute of Helminthology named after
K.I. Skryabin
Russian Federation
scientific advisor
Russian Federation
scientific advisor
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Review
For citations:
Poselov D.S., Arisov M.V. Toxicological and therapeutic assessment of «Сoсtsidon suspension 5 %» at coccidiosis in pigs. Russian Journal of Parasitology. 2014;(2):92-97. (In Russ.)
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