Preview

Russian Journal of Parasitology

Advanced search

Immunotoxic properties of insacar

Abstract

Immunotoxic properties of insacar are studied. By the results of reaction of hypersensitivity of the sloweddown type the stimulation index at the animals receiving insacar at the dose of 0,02 and 0,2 ml made respectively 9,45 and 9,79 unlike 10,18 in control that allows to conclude that the drug doesn't oppress the T-cellular link of immune system. Single application of insacar on skin in therapeutic and ten times increased therapeutic doses has no negative effect on the humoral immune answer.

About the Authors

A. A. Stepanov
Всероссийский научно-исследовательский институт гельминтологии им. К.И. Скрябина
Russian Federation


М. Арисов
Всероссийский научно-исследовательский институт гельминтологии им. К.И. Скрябина
Russian Federation


References

1. Даугалиева Э.Х. и др. Методические рекомендации по изучению влияния антгельминтиков на иммунный статус животных при гельминтозах. – М., 1989. –25 с.

2. Петров Р.В. Иммунология. – М.: Медицина, 1987.

3. Хаитов Р.М. и др. Методические указания по изучению иммунотропной активности фармакологических веществ. – 1998. – 34 с.

4. Kitamura K. A footpad weight assay method to evaluate delayed-type hypersensitivity in the mouse // Immunol. Methods. – 1980. – V. 39, № 3. – P. 277–283.

5. Sever J.L. Application of a micro-technique to viral serological investigations // J. Immunol. – 1962. – V. 88, № 1. – P. 398–413.


Review

For citations:


Stepanov A.A.,   Immunotoxic properties of insacar. Russian Journal of Parasitology. 2013;(4):104-108. (In Russ.)

Views: 335


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1998-8435 (Print)
ISSN 2541-7843 (Online)