Persistent activity and therapeutic efficacy of Delcid® 7.5 against scab mites (Psoroptes ovis) in sheep
https://doi.org/10.31016/1998-8435-2022-16-4-468-474
Abstract
The purpose of the research is to study persistent activity and therapeutic efficacy of Delcid® 7.5 against scab mites Psoroptes ovis in sheep.
Materials and methods. The studies were performed in the Bukhty peasant farm enterprise in November 2021 on the Kizlyarsky District winter pastures in the Republic of Dagestan. Three groups of sheep were formed, of which two groups (second and third) had a confirmed clinical diagnosis of psoroptic mange (P. ovis) and one group (first) was free from scab mites. Sheep from the first and second groups were treated with Delcid at a dose of 10 ml of the drug per animal. After 10 days, sheep from the second group were treated with the drug repeatedly at the same dose. Sheep from the first and second groups were treated with the drug applied on dry and intact skin of the back along the spine using the drop method. The third control (infected) group of animals was not treated. All experimental groups of sheep were kept in a common flock. The Delcid persistent activity and thera-peutic efficacy were evaluated by clinical examination and microscopy of the skin for P. ovis mites before the experiment started and at 1, 3, 7, 10, 14, 21, 25 and 30 days after treatment in the first group and at 1, 3, 7, 11, 13, 17, 20, 24, 31, 35 and 40 days in the second and third groups of sheep.
Results and discussion. It was found that Delcid 7.5 showed persistent activity in sheep against psoroptic mange pathogens for 21 days after a single treatment at a dose of 10 ml per animal. Delcid acaricidal effect after double treatment against P. ovis was 31 days.
About the Authors
S. V. EngashevRussian Federation
Engashev Sergey V., academician of the RAS, professor
109472, Moscow, Academician Scriabin Str., 23
E. S. Engasheva
Russian Federation
Engasheva Ekaterina S., candidate of veterinary science
109428, Moscow, Ryazansky prospect, 24 (1)
V. I. Kolesnikov
Russian Federation
Kolesnikov Vladimir I., doctor of veterinary science, professor
355017, Stavropol, Zootekhnichesky lane, 15
B. M. Bagamaev
Russian Federation
Bagamaev Bagama M., doctor of veterinary science, assistant professor
355017, Stavropol, Zootechnichesky lane
R. J. Ustarov
Russian Federation
Ustarov Rasul J.
367014, Republic of Dagestan, Makhachkala, Dakhadaeva Str., 28
References
1. Akbayev R. M., Vasilevich F. I., Bagamaev B. M. Epizootological process in psoroptic mange, mallophagosis and sifunculatosis in ruminants. Rossiyskiy veterinarnyy zhurnal. Sel'skokhozyaystvennyye zhivotnyye = Russian Journal of Veterinary Medicine. Livestock Animals. 2015; 3: 8-9. (In Russ.)
2. Bagamaev B. M., Vasilevich F. I. Influence of feeding and housing conditions on the development of skin diseases in sheep. Veterinarnyy vrach = Veterinarian. 2012; 1: 57-58. (In Russ.)
3. Bagamaev B. M. Spread of dermatitis of parasitic origin in sheep on farms in the North Caucasus. Rossiyskiy parazitologicheskiy zhurnal = Russian Journal of Parasitology. 2014; 3: 15-19.
4. Burmistrova M. I., Vasilevich F. I. Homeostasis of the rabbit’s body associated with Delcid®7.5. Vestnik Nizhegorodskoy gosudarstvennoy sel'skokhozyaystvennoy akademii = Bulletin of the Nizhny Novgorod State Agricultural Academy. 2021; 1 (29): 32-35. (In Russ.)
5. Burmistrova M. I., Engashev S. V., Engasheva E. S., Kolesnikov V. I., Koshkina N. A., Filimonov D. N. Insecticidal efficacy of Delcid 7.5 against mallophagosis of sheep. Mezhdunarodnyy vestnik veterinarii = International Bulletin of Veterinary Medicine. 2020; 4: 19-23. (In Russ.) https://doi.org/10.17238/issn2072-2419.2020.4.19
6. Engashev S. V., Engasheva E. S., Koshkina N. A., Kolesnikov V. I., Aliev M. A., Nikanorova A. L. Delcid 7.5 is an effective drug against ixodid ticks of cattle. Veterinariya i kormleniye = Veterinary Medicine and Feeding. 2020; 3: 12-14. (In Russ.) https://doi.org/10.30917/ATT-VK-1814-9588-2020-3-3
7. Engashev S. V., Engasheva E. S., Kolesnikov V. I., Koshkina N. A., Filimonov D. N. Insecticidal and repellant activities of Delcid® 7.5 against wolfarthiosis of sheep. Mezhdunarodnyy vestnik veterinarii = International Bulletin of Veterinary Medicine. 2021; 4: 70-74. (In Russ.) https://doi.org/10.52419/issn2072-2419.2021.4.70
8. Piskareva N. A., Vozgorkova E. O. Modern drugs used to treat myiasis in cattle. «Sovremennyye problemy nauki i obrazovaniya»: materialy XI Mezhdunarodnoy studencheskoy nauchnoy konferentsii = "Modern issues of science and education": materials of the XI International Student Scientific Conference. 2019; 46-47. (In Russ.)
9. Ramzaeva Yu. S., Filippov D. S. Therapeutic effect of synthetic pyrethroids against ectoparasites of cattle. «Nauchno-prakticheskiye tendentsii i aspekty APK Yuga Rossii»: sbornik nauchnykh trudov studentov, aspirantov i molodykh uchenykh = "Scientific and practical trends and aspects of the agro-industrial complex of the South of Russia": a collection of scientific papers of students, postgraduate students and young scientists. Stavropol, 2018; 78-80. (In Russ.)
10. Skvortsova D. M. Testing of synthetic pyrethroid drugs against parasitic dermatitis in cattle. «Innovatsii v proizvodstve, khranenii i pererabotke sel'skokhozyaystvennoy produktsii»: materialy II nauchno-prakticheskoy konferentsii studentov, aspirantov i molodykh uchenykh = "Innovations in the production, storage and processing of agricultural products": materials of the II Scientific and Practical Conference of students, postgraduate students and young scientists. 2016; 91-94. (In Russ.)
11. Ectoparasites of animals / Textbook / Under general editorship of V. I. Trukhachev. Stavropol: AGRUS, 2004; 372.
12. Chen Z., van Mol W., Vanhecke M., Duchateau L., Claerebout E. Acaricidal activity of plant-derived essential oil components against Psoroptes ovis in vitro and in vivo. Parasites & Vectors. 2019; 12 (1): 425. https://doi.org/10.1186/s13071-019-3654-x.
13. Hamel D., Joachim A., Löwenstein M., Pfister K. et al. Treatment and control of bovine sarcoptic and psoroptic mange infestation with ivermectin longacting injectable (IVOMEC(®) GOLD). Parasitol. Res. 2015; 114 (2): 535-42. https://doi.org/10.1007/s00436-014-4215-z.
14. Sturgess-Osborne C., Burgess S., Mitchell S., Wall R. Multiple resistance to macrocyclic lactones in the sheep scab mite Psoroptes ovis. Vet. Parasitol. 2019; 272: 79-82. https://doi.org/10.1016/j.vetpar.2019.07.007.
15. Van Mol Wouter, De Wilde Nathalie, Casaert Stijn and et. all. Resistance against macrocyclic lactones in Psoroptes ovis in cattle. Parasites & Vectors. 2020; 13: 127. https://doi.org/10.1186/s13071-020-04008-2.
Review
For citations:
Engashev S.V., Engasheva E.S., Kolesnikov V.I., Bagamaev B.M., Ustarov R.J. Persistent activity and therapeutic efficacy of Delcid® 7.5 against scab mites (Psoroptes ovis) in sheep. Russian Journal of Parasitology. 2022;16(4):468-474. (In Russ.) https://doi.org/10.31016/1998-8435-2022-16-4-468-474