Therapeutic efcacy of preparations in the form of a solution for external use based on imidacloprid, pyriproxyfen and moxidectin at nematodosis of dogs and cats
https://doi.org/10.31016/1998-8435-2022-16-2-243-251
Abstract
The purpose of the research is to study the therapeutic efcacy of drugs in the form of a solution for external use based on imidacloprid, pyriproxyfen and moxidectin against gastrointestinal nematodes and Diroflaria spp. microflaria in dogs and cats.
Materials and methods. . The studies were carried out on the basis of VNIIP (fl. Federal State Budgetary Scientifc Institution FNTs VIEV RAS) on dogs and cats of different sex and age, body weight spontaneously infected with parasites. The diagnosis, as well as the effectiveness of the drugs, was confrmed in a complex manner based on the anamnestic and epizootological data, the clinical picture and laboratory research methods (detection of helminth eggs in the animal's feces using the Fülleborn method with subsequent differentiation, microscopy of animal blood smears to detect microflariae). To rule out infection of animals (dogs) with babesia, blood samples were taken and a laboratory analysis was performed to detect parasites (Babesia canis).
Results and discussion. 100% effectiveness of Insacar Total C (for dogs) and Insacar Total K (for cats) has been established for nematodes of the gastrointestinal tract (toxocarosis, toxascariosis, uncinariosis, hookworm, trichuriosis) and diroflariosis (the initial stage of the disease). Side effects and complications after treatment of animals with drugs were not revealed
About the Authors
O. N. Tochieva
All-Russian State Center for Quality and Standardization of Medicinal Products for Animals and Feed (VGNKI)
Russian Federation
Russian Federation
Tochieva Oksana N.,applicant
28, Bolshaya Cheremushkinskaya st., Moscow, 117218
M. V. Arisov
All-Russian Scientifc Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientifc Institution “Federal Scientifc Centre VIEV”
Russian Federation
Russian Federation
Arisov Mikhail V., Doctor of Veterinary Sciences, Professor of the Russian Academy of Sciences
28, Bolshaya Cheremushkinskaya st., Moscow, 117218
References
1. Arisov M. V., Indyukhova E. N., Kuznetsova E. A., Arisova G. B., Smirnova E. S. Helmintal tablets – a new complex drug based on moxidectin and praziquantel for the treatment of endoparasitosis in dogs. Uchenyye zapiski Kazanskoy gosudarstvennoy akademii veterinarnoy meditsiny imeni N. E. Baumana = Scientifc notes of the Kazan State Academy of Veterinary Medicine named afer N. E. Bauman. 2015; 223 (3): 12-15. (In Russ.)
2. Arisov M. V., Belykh I. P., Artemov V. V. Inspector Quadro – the complex of preparation for the treatment of ectoand endoparasitoses in cats and dogs. Rosiyskiy parazitologicheskiy zhurnal = Russian Journal of Parasitology. 2018; 12 (2): 75–84. (In Russ.) https://doi.org/10.31016/1998-8435-2018-12-2-75-84
3. Arisova G. B. Efciency of the preparation of the prolonged action on the basis of moxidectin "Neoterica Protecto Syrup" in ecto- and endoparasitosis of carnivore animals. «Teoriya i praktika bor'by s parazitarnymi boleznyami»: sbornik nauchnykh statey po materialam Mezhdunarodnoy nauchnoy konferentsii = "Teory and practice of combating parasitic diseases": a collection of scientifc articles based on the materials of the International Scientifc Conference. 2021; 22: 74-79. (In Russ.) https://doi.org/10.31016/978-5-6046256-1-3
4. Belykh I. P., Arisova G. B. Treatment of dogs’ and cats’ diroflariosis with complex antiparasitic drugs. Rossiyskiy parazitologicheskiy zhurnal = Russian Journal of Parasitology. 2019; 13 (1): 52–55. (InRuss.) https://doi.org/10.31016/1998-8435-2019- 13-1-52-55
5. Bespalova N. S. Epizootology of a number of helminthoses in dogs in the city. Veterinary medicine. 2003; 1: 31-32. (In Russ.)
6. Volichev A. N., Gorokhov V. V. Helminths and protozoa of carnivores in the metropolis of Moscow. Veterinary medicine. 1999; 11: 7-9. (In Russ.)
7. Gorin M. A., Karelkin D. V., Pashkin A. V. et al. Epizootological monitoring of the development of the epizootic situation in the conditions of the Nizhny Novgorod region. Intl. scientifc and practical. conf. N. Novgorod, NGSKhA, 2013; 402.
8. Zolotykh T. A. Modern methods of laboratory diagnostics of carnivorous diroflariasis. Proceedings of the Kostroma State Agricultural Academy. 2015; 82: 62-66.
9. Yastreb VB Cat diroflariasis in Moscow. "Teory and practice of combating parasitic diseases": materials of the reports of the scientifc conference of the All-Russian Society of Helminthologists of the Russian Academy of Sciences. 2005; 6: 415-417.
10. Yastreb V. B., Arkhipov I. A. Recommendations for the diagnosis, treatment and prevention of diroflariasis in dogs in the Moscow region. Rosiyskiy parazitologicheskiy zhurnal = Russian Journal of Parasitology. 2008; 4: 109-114.
11. Litster A. L., Atwell R. B. Feline heartworm disease: a clinical review. Journal of Feline Medicine and Surgery. 2008; 10 (2): 137-144.
12. McCall J. W., Genchi C., Kramer L. H., et al. Heartworm disease in animals and humans. Advances in parasitology. 2008; 66. 193-285
Review
For citations:
Tochieva O.N., Arisov M.V. Therapeutic efcacy of preparations in the form of a solution for external use based on imidacloprid, pyriproxyfen and moxidectin at nematodosis of dogs and cats. Russian Journal of Parasitology. 2022;16(2):243-251. (In Russ.) https://doi.org/10.31016/1998-8435-2022-16-2-243-251
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