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FMRFamid-like neuropeptides as modulators of locomotory reactions in plant parasitic cyst nematodes

https://doi.org/10.31016/1998-8435-2022-16-1-50-62

Abstract

The purpose of the research is analysis of world literature dedicated to studies of physiological role and functional importance of FMRFamide-like neuropeptides – components of peptidergic nervous system in cyst nematode plant parasites using an example of 2nd stage larvae of potato and soy nematodes Globodera pallida and Heterodera glycines.
The main physiological and functional characteristics of endogenous FMRFamid-like neuropeptides had been found in studies of functional role of flp genes expression of which was discovered in various nerve structures of potato and soy nematodes. The work shows the role of endogenous FMRFamid-like neuropeptides in such plant nematodes' behavior elements as locomotions promoting the parasites' life activity. The functional importance of flp genes coding these biologically active substances and possibilities of using data on physiological effects of neuropeptides on plant nematodes' activity for development of new anthelminthic precise effect drugs are discussed.

About the Authors

T. A. Malyutina
Center of Parasitology, A. N. Severtsov's Institute of Ecology and Evolution Russian Academy of Science
Russian Federation

Candidate of Biological Sciences

33, Leninsky Prospekt, Moscow, 119071 



M. V. Voronin
Center of Parasitology, A. N. Severtsov's Institute of Ecology and Evolution Russian Academy of Science
Russian Federation

Candidate of Biological Sciences

33, Leninsky Prospekt, Moscow, 119071 



References

1. Plant parasitic nematodes of Russia. Eds. S. V. Zinovieva, V. N. Chizhov. Moscow, KMK Ltd., 2012; 386. (In Russ.)

2. Atkinson H. J., Isaac R. E., Harris P. D., Sharpe C. M. FMRFamide-like immunoreactivity within the nervous system of the nematodes Panagrellus redivius, Caenorhabditis elegans and Heterodera glycines. J. Zool., Lond. 1988; 216. 663-671.

3. Atkinson L. E., Stevenson M., Mckoy C. J., Marks N. J., Fleming C., Zamanian M., Day T. A., Kimber M. J., Maule A. G., Mousley A. Flp-32 Ligand/Receptor Silencing Phenocopy Faster Plant Pathogenic Nematdes. PLoS Patog. 2013; 9 (2): 1003169. https://doi.org/10.1371/joumal.ppat. 1003169.

4. British Ecological Society (BES): 2009. Biological Control of Plant Parasitic Nematodes http://britishecologicalsociety.org/blog/blog/2009/01/20/biological-control-of plant-parasitic-nematodes Retrieved. 2009.

5. Covden C., Stretton A.O.W. AF2, an Ascaris neuropeptide: isolation, sequence bioactivity. Peptides. 1993; 14. 423-430.

6. Covden C., Stretton A.O.W. Eight novel FMRFamide-like neuropeptides isolated from the nematode Ascaris sum. Peptides. 1995;16. 491-500.

7. Coons A. H., Leduc E. H., Connolly J. M. Studies of antibody production. I. // A method for the histochemical demonstration of specific antibody and its application to a study for the hyperimmune rabbit. J. Exper. Med. 1955; 102. 49-60.

8. Fire A. Si Qun Xu, Montgomery M. K., Kostas S. A., Driver S. E., Mello C. C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998; 391. № 6669. 806-811.

9. Geary T. G., Marks N. J., Maule A. G., Bowman J. W., Alexander-Bowman S. J., Day T. A., Larsen M. J., Kubiak M., Davis P., Thompson D. P. Pharmacology of FMRFamide-related peptides in helminths. Annals of the New York Academy of Science. 1999; 897. 217-227.

10. Johnston M.J.G. Veigh P. M., Masler S., Fleming C. C, Maule A. G. FMRFamide-like peptides in root-knot nematodes and their potential role in nematode physiology. J. оf Helminthology. 2010; 84. 253-265. https://doi.org/10.1017/S0022149X09990630

11. Kaeting C., Thorndyke M. C., Holden-Dye L., Williams R. G., Walker R. J. The isolation of FMRFamide-like peptide from the nematode Haemonchus contortus. Parasitology. 1995; 111. 515–521.

12. Kimber M. J., Fleming C. C., Bjourson A. J., Halton D. W., Maule A. G. FMRFavmide-related peptides in potato cyst nematodes. Molecular and Biochemical Parasitology. 2001; 116 (2): 199-208.

13. Kimber M. J., Fleming C. C., Prior A., Halton D. W., Maule A. G. Localisation of Globodera pallid FMRFamide-related peptide encoding genes using in situ hybridization. Int. J. Parasitol. 2002; 32 (9): 1095-1105.

14. Kimber M. J., Fleming C. C. Neuromuscular function in plant parasitic nematodes: a target for novel control stratеgies? Parasitology. 2005; 131. 129–142. https://doi.org/10.1017/S0031182005009157

15. Kimber M. J., McKinney S., McMaster S., Day T. A., Fleming C. C., Maule A. G. Flp-gene disruption in parasitic nematode reveals motor dysfunction and unusual neuronal sensivity to RNA interference. FASER J. 2007; 21. 1233-1243. https://doi.org/10.1096/fj.06-7343com

16. McVeigh P., Geary T. G., Marks N. J., Maule A. G. The FLP-side of nematodes. TRENDS in Parasitology. 2006; 22. 385-396. https://doi.org/10.1016/j.pt.2006.06.010

17. Masler E. P., Kovaleva E. S., Sardanelli S. FMRFamide-like Immunoactivity in Heterodera glycines (Nemata: Tylenchida). J. оf Nematology. 1999; 31 (2): 224-231.

18. Marks N. J., Sangster N. C., Maule A. G., Halton D. W., Thompson D. P., Geary T. G., Shaw C. Structural characterization and pharmacology of KНEYLRFamide (AF2) and KSAYMRFamide (PF3/АF8) from Haemochus contortus. Mol. Biochem. Parasitol. 1999; 100. 185-194.

19. Marks N. J., Maule A. G., Geary T. G., Thompson D. P., Halton D. W., Shaw C. KSAYMRFamide (PF3/АF8) is present in the free-living nematode, Caenorhabditis elegans. Biochem. Biophys. Res. Commun. 1998; 248. 422-425.

20. Masler E. P. Behaviour of Heterodera glycines and Meloidogyne incognita infective juveniles exposed to nematode FMRFamide-like peptides in vitro. Nematology. 2012; 14 (5): 605-612. https://doi.org/10.1163/156854111X617879

21. Maule A. G., Mousley A., Marks N. J., Day T. A., Thompson D. P., Geary T. G., Halton D. W. Neuropeptide signaling systems – potential drug targets for parasite and pest control. Curr. Top. Med. Chem. 2002; 2. 733–758. https://doi.org/10.2174/1568026023393697

22. Maule A. G., Shaw C., Bowman J. W., Halton D. W., Thompson D. P., Geary T. G., Thim L. FMRFamide-like peptide AF2 (Ascaris suum) is present in the free-living nematode Panagrellus redivivus (Nematoda, Rhabditida). Parasitology. 1994; 109. 351-356.

23. Mertens I., Vandigenen A., Meeusen T., Janssen T., Luyten W., Nachman R.J., Loof A.D., Schoofs L. Functional characterization of the putative orphan neuropeptide G-protein coupled receptor C26F1.6 in Caenorhabditis elegans. FEBS Lett. 2004; 573 (1 -3): 55-60. https://doi.org/10.1016/j.febslet.2004.07.058

24. Peymen K., Watteyne J., Frooninckx L., Schoofs L., Beets I. The FMRFamide-like peptide family in nematodes. Frontiers in endocrinology. 2014; 5. Art. 90. 1-21. https://doi.org/10.3389/fendo.2014.00090

25. Price D. A., Greenberg M. J. Structure of a molluscan cardio excitatory neuropeptide. Science. 1977; 197. 670-671.

26. White J. D., Southgate E., Thompson J. N., Brenner S. The structure of the nervous system of Caenorhbditis elegans. Philosophical Transactions of the Royal Society of London. 1986. Series B. 314. 1-340.


Review

For citations:


Malyutina T.A., Voronin M.V. FMRFamid-like neuropeptides as modulators of locomotory reactions in plant parasitic cyst nematodes. Russian Journal of Parasitology. 2022;16(1):50-62. (In Russ.) https://doi.org/10.31016/1998-8435-2022-16-1-50-62

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ISSN 1998-8435 (Print)
ISSN 2541-7843 (Online)