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Treatment of Dogs’ and Cats’ Dirofilariosis with Complex Antiparasitic Drugs

https://doi.org/10.31016/1998-8435-2019-13-1-52-55

Abstract

The purpose of the research is to study efficiency of drugs for veterinary use "Inspector Quadro C” and "Inspector Quadro K” in the case of dogs’ and cats’ dirofilariosis.

Materials and methods. Study was conducted on 24 animals of different breeds, which were naturally infected by Dirofilaria immitis and D. repens, including 12 dogs at the age from 7 weeks to four years with the body weight of 6–20 kg, and 12 cats at the age from 7 weeks to two years with the body weight of 0.7–5 kg. Diagnosis as well as drug efficiency was confirmed in its entirety based on clinical signs and laboratory studies (microscopic evaluation of animals’ blood films). V. B. Yastreb concentration method were used as the method of study. The drug was administered to the animals from experimental group by applying on dry, uninjured skin on places inaccessible for licking off in the dose range of 0.1 ml per 1 kg of animal body weight twice at intervals of 10–14 days which corresponds to the dose for cats 1 mg/kg, for dogs 2.5 mg/kg for moxidectin.

Results and discussion. It has been established that drugs "Inspector Quadro C” and "Inspector Quadro K” had demonstrated 100 % efficiency at dirofilariosis disease in dogs and cats. Negative influence of drugs on animals’ organisms was not established.

About the Authors

I. P. Belykh
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants – a branch of Federal State Budgetary Institution of Science "Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary Medicine named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences"
Russian Federation

Irina P. Belykh

28, B. Cheremushkinskaya Street, Moscow, 117218



G. B. Arisova
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants – a branch of Federal State Budgetary Institution of Science "Federal Scientific Center – All-Russian Scientific Research Institute of Experimental Veterinary Medicine named after K. I. Skryabin and Ya. R. Kovalenko of the Russian Academy of Sciences"
Russian Federation

Gulnara B. Arisova

28, B. Cheremushkinskaya Street, Moscow, 117218



References

1. Arisov M. V., Indyukhova E. N., Arisova G. B. Evaluation of antiparasitic efficiency of drugs "Inspector Quadro C" and "Inspector Quadro K". Veterinariya, zootekhniya i biotekhnologiya = Veterinary science, zootechny and biotechnology. 2015; 9: 6–10. (In Russ.)

2. Arisov M. V., Indyukhova E. N., Kuznetsova E. A., Arisova G. B., Smirnova E. S. Gelmintal tablets the new complex moxidectin and praziquantelbased drug for treatment dogs’ endoparasitosis. Transactions of Kazan State Academy of Veterinary Science named after N. E. Bauman. 2015; 223(3): 12–15. (In Russ.)

3. Arkhipov I. A., Arkhipova D. R. Dirofilariosis. 2004; 194 s (In Russ.).

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7. Skovorodin E. N., Paramonov V. V. Lifetime and pathomorphological diagnostics of dogs’ dirofilariosis. Transactions of Educational Establishment Vitebsk State Academy of Veterinary Medicine. 2011; 47(2): 97–99. (In Russ.)

8. Yastreb V. B. Comparison studies of methods of detection microfilaria in dogs’ blood. Materials of research and practice conference of All-Russian Helminthologists community of Russian Academy of Sciences “The theory and practice of protection from parasitic diseases”. 2004: 443–445. (In Russ.)

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Review

For citations:


Belykh I.P., Arisova G.B. Treatment of Dogs’ and Cats’ Dirofilariosis with Complex Antiparasitic Drugs. Russian Journal of Parasitology. 2019;13(1):52-55. (In Russ.) https://doi.org/10.31016/1998-8435-2019-13-1-52-55

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ISSN 1998-8435 (Print)
ISSN 2541-7843 (Online)