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СOMPARATIVE EFFICACY OF SOME IVERMECTIN-BASED DRUGS APPLIED FOR TREATMENT OF NEMATODOSIS IN HORSES

Abstract

The comparative efficacy of some ivermectin-based drugs applied for treatment of nematodosis in horses has been investigated. Preparations were tested on 69 horses, 41 of them were spontaneously infected with Strongylata, 26 – with Parascaris and 2 – with Anoplocephala. Alezan paste at a dose of 0,2 mg/kg of ivermectin and 1 mg/kg of praziquantel was administered orally to 26 horses. 30 horses received Prasiver suspension at the same dose with food. Horses of the 3rd group received orally Bimectin paste at a recommended dose of 0,2 mg/kg of ivermectin. 6 horses that didn’t get a preparation served as a control group. The efficacy of preparations has been estimated according to the results of feces examination carried out before and 10 and 20 days after dehelmintization. Alezan and Bimectin paste demonstrated a 100% efficacy of these drugs in the treatment of strongylatosis and parascaridosis in horses. Prasiver suspension shown a 100% efficacy in the treatment of strongylatosis and 72,7% – by parascaridosis in case of reduction in number of Parascaris equorum eggs from 501 to 110 expl. per 1 kg feces. Two horses infected with Anoplocephala were free of Anoplocephala perfoliata infection after treatment with Alezan and Praziquantel. All preparations are well - tolerated by horses and do not cause any side effects. 

About the Authors

L. A. BUNDINA
All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K. I. Skryabin
Russian Federation

PhD of veterinary sciences 

117218, 28 Bolshaya Cheremushkinskaya



E. E. YEVSTAFYEVA
Central Moscow race track
Russian Federation

veterinarian 



References

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2. Velichkin, P. A. Prizhiznennaja diagnostika delafondioza, al'fortioza, strongileza i trihonematidozov loshadej po invazionnym lichinkam / P. A. Velichkin. – M., 1954.

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4. Karns, P. A. A survey of adverse effects associated with ivermectin use in Louisiana horses / P. A. Karns, D. G. Luther // J. of the Am. Vet. Med. Assoc. – 1984. – V. 185, № 7. – P. 782–783.


Review

For citations:


BUNDINA L.A., YEVSTAFYEVA E.E. СOMPARATIVE EFFICACY OF SOME IVERMECTIN-BASED DRUGS APPLIED FOR TREATMENT OF NEMATODOSIS IN HORSES. Russian Journal of Parasitology. 2014;(4):74-78. (In Russ.)

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ISSN 1998-8435 (Print)
ISSN 2541-7843 (Online)