ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS)
Abstract
The anticoagulant effect of salivary secretion of ticks Argas persicus was studied. The experiments were conducted on aorta preparations isolated from the chest of white outbread rats. Isometric contraction in an isolated muscle preparation was registered by mechanotron. To determine the anticoagulant mechanism of blood plasma at deficiency of factors X, XI, IX and VIII we used the activated partial thromboplastin time. It was determined that the process of blood coagulation in rats slows down. The coagulation values depend on the concentration of tested secretions. It was found that at concentration 150 mkg /ml, the blood coagulation rate fell to 78,4 %. The role of calcium ions in regulation of vascular smooth muscle cells (VSMCs) contraction was determined. The components of salivary glands A. Persicus have a relaxation effect on the contraction of rat aortic ring preparation
About the Authors
A. U. Mirzayeva
The Institute of Gene Pool of Plants and Animals world of Uzbekistan Academy of Sciences,
100053 Uzbekistan, Tashkent, 232 Bogishamol st.
Uzbekistan
Uzbekistan
F. D. Akramova
The Institute of Gene Pool of Plants and Animals world of Uzbekistan Academy of Sciences,
100053 Uzbekistan, Tashkent, 232 Bogishamol st.
Uzbekistan
Uzbekistan
S. Sh. Hushmatov
Scientific Institute of Bioorganic Chemistry named after A.S. Sadykov, Academy of Sciences of
Republic Uzbekistan, 100170 Tashkent, 83. Mirzo Ulugbek st.
Uzbekistan
Uzbekistan
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Review
For citations:
Mirzayeva A.U., Akramova F.D., Hushmatov S.Sh. ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS). Russian Journal of Parasitology. 2016;35(1):24-29. (In Russ.)
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