Analysis of morphological and biochemical parameters of the blood of dogs infected with leishmaniasis in the Republic of Cyprus
https://doi.org/10.31016/1998-8435-2025-19-4-500-507
Abstract
The purpose of the research is to investigate the clinical, morphological, and biochemical parameters of the peripheral blood of dogs with a confirmed diagnosis of leishmaniasis in the Republic of Cyprus.
Materials and methods. We studied the morphological and biochemical parameters of the blood of eight hunting dogs weighing 15–23 kg, kept in private enclosures or outdoors in Paphos (Cyprus), infected with leishmaniasis. Diagnosis of the presence of antibodies to the parasite was established using the SNAP test (IDEXX, USA), an enzyme-linked immunosorbent assay. An IDEXX ProCyte Dx hematology analyzer was used for clinical blood analysis, and biochemical blood tests were performed on an IDEXX Catalyst Dx analyzer.
Results and discussion. It was found that most dogs infected with leishmaniasis exhibited both general negative changes in blood cells, body systems, and target organs, as well as individual changes. General changes in the peripheral blood of dogs include erythrocytopenia, decreased hemoglobin, increased creatinine, urea, and phosphorus levels, which may indicate the development of acute renal failure, as well as increased alanine aminotransferase and alkaline phosphatase activity.
About the Authors
A. Parides
Moscow State Academy of Veterinary Medicine and Biotechnology named after K. I. Skryabin
Россия
Россия
Parides Antonis, PhD student, Department of Parasitology and Veterinary-Sanitary Expertise
Moscow
E. A. Shemyakova
Moscow State Academy of Veterinary Medicine and Biotechnology named after K. I. Skryabin
Россия
Россия
Shemyakova Svetlana A., Doctor of Veterinary Sciences, Acting Head of the Department of Parasitology and VeterinarySanitary Expertise
Scopus ID: 57218879581
Moscow
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Review
For citations:
Parides A., Shemyakova E.A. Analysis of morphological and biochemical parameters of the blood of dogs infected with leishmaniasis in the Republic of Cyprus. Russian Journal of Parasitology. 2025;19(4):500-507. (In Russ.) https://doi.org/10.31016/1998-8435-2025-19-4-500-507
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