Efficacy of micronized dosage forms of fenbendazole at bothryocephalosis of carp
https://doi.org/10.31016/1998-8435-2024-18-4-441-448
Abstract
The purpose of the research is to develop and test new dosage forms of fenbendazole for carp bothriocephalosis.
Materials and methods. A formulation of four dosage forms based on fenbendazole has been developed. Laboratory lots of therapeutic feeds with dosage forms have been produced, the degree of fish infection with bothriocephalosis during the growing season and the efficacy of testing micronized dosage forms for carp bothriocephalosis have been established according to generally accepted methods. The efficacy of using micronized dosage forms at different feeding rates has been assessed.
Results and discussion. When using four micronized dosage forms of fenbendazole in therapeutic granulated compound feeds for carp bothriocephalosis, the most effective was the therapeutic feed with a 6% micronized dosage form of fenbendazole given once at a 5% feeding rate. This dosage form of fenbendazole has shown an efficiency close to microsal, which is currently used for the treatment of bothriocephalosis in carp.
Supporting agencies: The work was carried out with the financial support of the Ministry of Education and Science of the Russian Federation within the framework of the Fundamental Scientific Research Program of the State Academies of Sciences, which forms the basis of the state assignment No. FGUG-2022-0012 without attracting additional sources of funding.
About the Author
T. A. Vasilyeva
All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution “Federal Scientific Centre VIEV” (VNIIP – FSC VIEV)
Russian Federation
Russian Federation
Tatiana A. Vasilyeva, PhD in Veterinary Sciences, Leading Researcher at the Laboratory of Experimental Therapy
Researcher ID: U-5444-2018, Scopus ID: 57302787500
Moscow
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For citations:
Vasilyeva T.A. Efficacy of micronized dosage forms of fenbendazole at bothryocephalosis of carp. Russian Journal of Parasitology. 2024;18(4):441-448. (In Russ.) https://doi.org/10.31016/1998-8435-2024-18-4-441-448
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