vniigisРоссийский паразитологический журналRussian Journal of Parasitology1998-84352541-7843ВНИИП – филиал ФГБНУ ФНЦ ВИЭВ РАН10.31016/1998-8435-2022-16-1-50-62vniigis-865Research ArticleОБЗОРЫREVIEWSFMRFамид-подобные нейропептиды – модуляторы локомоторных реакций у растительных цистообразующих паразитических нематодFMRFamid-like neuropeptides as modulators of locomotory reactions in plant parasitic cyst nematodesМалютинаТ. А.MalyutinaT. A.

 кандидат биологических наук 

 119071, г. Москва, Ленинский проспект, 33 

Candidate of Biological Sciences

33, Leninsky Prospekt, Moscow, 119071 

maliytina@mail.ruВоронинМ. В.VoroninM. V.

 кандидат биологических наук 

 119071, г. Москва, Ленинский проспект, 33 

Candidate of Biological Sciences

33, Leninsky Prospekt, Moscow, 119071 

voronin_mike@mail.ruЦентр паразитологии Института проблем экологии и эволюции им. А. Н. Северцова Российской академии наукРоссияCenter of Parasitology, A. N. Severtsov's Institute of Ecology and Evolution Russian Academy of ScienceRussian Federation2022150320221615062Copyright © Малютина Т.А., Воронин М.В., 20222022Малютина Т.А., Воронин М.В.Malyutina T.A., Voronin M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://vniigis.elpub.ru/jour/article/view/865

Цель исследований: анализ зарубежной литературы по изучению физиологической роли и функционального значения FMRFамид-подобных нейропептидов, которые являются компонентами пептидергической нервной системы у цистообразующих нематод – паразитов растений на примере личинок 2-го возраста картофельной и соевой нематод Globodera pallida и Heterodera glycines.Основные физиологические и функциональные характеристики эндогенных FMRFамид-подобных нейропептидов получены в результате исследований функциональной роли генов (flp-гены), экспрессия которых выявлена в различных нервных структурах картофельной и соевой нематод. Показана роль эндогенных FMRFамид-подобных нейропептидов в таких поведенческих реакциях фитонематод, как локомоции, которые обеспечивают жизнедеятельность растительных паразитов. Обсуждается функциональное значение flp-генов, кодирующих эти биологически активные вещества, и возможность использования данных о физиологических эффектах нейропептидов на двигательную активность фитонематод при разработке новых антигельминтных препаратов направленного действия.

The purpose of the research is analysis of world literature dedicated to studies of physiological role and functional importance of FMRFamide-like neuropeptides – components of peptidergic nervous system in cyst nematode plant parasites using an example of 2nd stage larvae of potato and soy nematodes Globodera pallida and Heterodera glycines.The main physiological and functional characteristics of endogenous FMRFamid-like neuropeptides had been found in studies of functional role of flp genes expression of which was discovered in various nerve structures of potato and soy nematodes. The work shows the role of endogenous FMRFamid-like neuropeptides in such plant nematodes' behavior elements as locomotions promoting the parasites' life activity. The functional importance of flp genes coding these biologically active substances and possibilities of using data on physiological effects of neuropeptides on plant nematodes' activity for development of new anthelminthic precise effect drugs are discussed.

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The authors declare that there are no conflicts of interest present.