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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vniigis</journal-id><journal-title-group><journal-title xml:lang="ru">Российский паразитологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Parasitology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-8435</issn><issn pub-type="epub">2541-7843</issn><publisher><publisher-name>ВНИИП – филиал ФГБНУ ФНЦ ВИЭВ РАН</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">vniigis-171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПАТОГЕНЕЗ, ПАТОЛОГИЯ И ЭКОНОМИЧЕСКИЙ УЩЕРБ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PATHOGENEZIS, PATHOLOGY AND ECONOMIC DAMAGE</subject></subj-group></article-categories><title-group><article-title>ПАТОМОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ В ОРГАНАХ ДЫХАНИЯ И НЕКОТОРЫЕ АСПЕКТЫ ПАТОГЕНЕЗА ПРИ ДИКТИОКАУЛЕЗЕ ЛОСЯ</article-title><trans-title-group xml:lang="en"><trans-title>PATHOMORPHOLOGICAL CHANGES IN THE RESPIRATORY ORGANS AND SOME ASPECTS OF THE PATHOGENESIS OF DICTYOCAULOSIS IN ELK</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Окулова</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Okulova</surname><given-names>I. I.</given-names></name></name-alternatives><email xlink:type="simple">oliabio@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жданова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhdanova</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">oliabio@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт охотничьего хозяйства и звероводства им. проф. Б. М. Житкова  610000, г. Киров, Преображенская, 79</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Prof. B. M. Zhitkov Russian Research Institute on Game Management and Fur Farming,   610000, Kirov, 79 Preobrazhenskaya st.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт  фундаментальной и прикладной паразитологии животных и растений им. К. И. Скрябина  &#13;
Москва, Б. Черемушкинская, 28</institution><country>Россия</country></aff><aff xml:lang="en"><institution>All-Russian Scientific Research Institute of Fundamental and Applied Parasitology of Animals and Plants named after K. I. Skryabin, 117218, Russia, 28 B. Cheremushkinskaya st.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>08</day><month>05</month><year>2016</year></pub-date><volume>0</volume><issue>3</issue><fpage>53</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Окулова И.И., Жданова О.Б., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Окулова И.И., Жданова О.Б.</copyright-holder><copyright-holder xml:lang="en">Okulova I.I., Zhdanova O.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vniigis.elpub.ru/jour/article/view/171">https://vniigis.elpub.ru/jour/article/view/171</self-uri><abstract><p>Цель исследования – изучение патоморфологических изменений в органах дыхания лося при диктиокаулезе.  Материалы и методы.  Проведено гельминтологическое вскрытие трупа лося, спонтанно инвазированного  Dictyocaulus eckerti. Для гистологического  исследования отобрали кусочки пораженных участков легких на границе со здоровой тканью. Материал фиксировали в 10%-ном водном растворе нейтрального формалина. Изготовление парафиновых гистологических срезов толщиной 5–7 мкм  проводили по общепринятым методикам. Срезы окрашивали гематоксилином и эозином. Микрофотосъемку осуществляли камерой «Digital» на микроскопе «Genaval».  Результаты  и обсуждение.  В  легких лося, инвазированного  D. eckerti,  выявлены существенные структурные изменения. Личинки D. eckerti обнаружены в гранулёмах в просветах мелких и средних бронхах.  При  патогистологическом  исследовании легких теленка лося обнаружено наличие множественных паразитарных гранулём, очагов гиперемии и кровоизлияний. В местах локализации паразита интерстициальная ткань легкого утолщена за счет инфильтрации лимфоидными клетками, эозинофилами, единичными нейтрофилами и  гистиоцитами и очагового разрастания соединительной ткани.  </p></abstract><trans-abstract xml:lang="en"><p>Objective of research: studying of pathomorphological changes in the  respiratory organs of elk with dictyocaulosis.  Materials and methods:    A helminthological autopsy of the elk spontaneously infected with Dictyocaulus eckerti was performed. The infected pieces of lung located close to the edge of the healthy tissue were used for histological examination. The material has been preserved in 10% neutral buffered formalin solution.  Paraffin histological sections having the 5–7 mkm thickness were produced according to the standard methods. The sections were stained with haematoxylin and eosin. The photomicrography was made with the camera  «Digital» on microscope «Genaval».  Results and discussion:  In lungs of the elk infected with  D. eckerti,  the  essential structural changes were detected. D. eckerti larvae were found in granulomas in the lumens of small and medium-sized bronchi. The pathohistological examination of lungs of the young elk allowed to detect multiple parasitic granulomas, hyperthermic and hemorrhagic foci. In places of parasite localization the lung interstitial tissue becomes thickened due to the infiltration by lymphoid, eosinophilic cells, single  neutrophils  and  histiocytes as well as due to the growth of connective tissue.  </p></trans-abstract><kwd-group xml:lang="ru"><kwd>лось</kwd><kwd>диктиокаулез</kwd><kwd>легкие</kwd><kwd>лимфоциты</kwd><kwd>гранулёма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>elk</kwd><kwd>dictyocaulosis</kwd><kwd>lungs</kwd><kwd>lymphocytes</kwd><kwd>granuloma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Афанасов В. И. О регионарности и топографии лимфоузлов у парнокопытных // Сб. раб. «Современные проблемы ветеринарной медицины». – Киров, 2003. – С. 5–7.</mixed-citation><mixed-citation xml:lang="en">Afanasov V. I.  On the regional belonging and topography  of lymph nodes in cloven-hoofed animals.  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