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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vniigis</journal-id><journal-title-group><journal-title xml:lang="ru">Российский паразитологический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Parasitology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-8435</issn><issn pub-type="epub">2541-7843</issn><publisher><publisher-name>ВНИИП – филиал ФГБНУ ФНЦ ВИЭВ РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31016/1998-8435-2026-20-1-63-72</article-id><article-id custom-type="elpub" pub-id-type="custom">vniigis-1425</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БИОХИМИЯ, БИОТЕХНОЛОГИЯ И ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BIOCHEMISTRY, BIOTECHNOLOGY AND DIAGNOSTICS</subject></subj-group></article-categories><title-group><article-title>Методы диагностики бабезиоза собак</article-title><trans-title-group xml:lang="en"><trans-title>Diagnostic methods for canine babesiosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6709-6180</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беломытцева</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belomyttseva</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беломытцева Евгения Сергеевна, младший научный сотрудник</p><p>Scopus ID: 57222568712</p><p>Москва</p></bio><bio xml:lang="en"><p>Belomyttseva Evgeniya S., Junior Researcher</p><p>Scopus ID: 57222568712</p></bio><email xlink:type="simple">belomyttseva@vniigis.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт фундаментальной и прикладной паразитологии животных и растений – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр – Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К. И. Скрябина и Я. Р. Коваленко Российской академии наук» (ВНИИП – фил. ФГБНУ ФНЦ ВИЭВ РАН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>All-Russian Scientific Research Institute for Fundamental and Applied Parasitology of Animals and Plant – a branch of the Federal State Budget Scientific Institution "Federal Scientific Centre VIEV"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>26</day><month>03</month><year>2026</year></pub-date><volume>20</volume><issue>1</issue><fpage>63</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беломытцева Е.С., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Беломытцева Е.С.</copyright-holder><copyright-holder xml:lang="en">Belomyttseva E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vniigis.elpub.ru/jour/article/view/1425">https://vniigis.elpub.ru/jour/article/view/1425</self-uri><abstract><p>Цель исследований – анализ современных методов диагностики бабезиоза собак, дифференциальной диагностики от других кровопаразитарных болезней.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Материалом для исследований служили многолетние данные литературы, которые были проанализированы и обобщены с освещением методов прижизненной диагностики бабезиоза собак.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Бабезиоз собак — это трансмиссивное, очень распространённое гемопротозойное заболевание, передаваемое иксодовыми клещами, которое встречается по всему миру. У собак основными переносчиками бабезиоза являются клещи родов Rhipicephalus, Dermatocentor, Haemaphysalis. Возбудители бабезиоза – одноклеточные простейшие округлой, овальной, грушевидной или амебовидной формы, которые передаются при укусе клеща, паразитируют внутри эритроцитов (в одном эритроците может быть от 1 до 32 особей), плазме крови, нейтрофилах, можно обнаружить и в паренхиматозных органах. Наиболее частыми осложнениями может быть гемолитическая анемия, тромбоцитопения, а также развитие почечной и печеночной недостаточности, обострение хронических заболеваний. Течение заболевания может быть острым, хроническим, субклиническим. Инкубационный период – от 3 до 21 дня. При субклинической форме возможны периодические обострения заболевания. Симптомы заболевания могут зависеть от степени течения заболевания. Наиболее частые симптомы при острой стадии заболевания – лихорадка, вялость, бледные или иктеричные слизистые оболочки, темная моча, анорексия. При исследованиях выявляют спленомегалию и гепатомегалию, в крови отмечают анемию, тромбоцитопению и моноцитоз. Для подтверждения заболевания используют микроскопию мазков крови, ПЦР исследования, ИФА диагностику.</p></sec></abstract><trans-abstract xml:lang="en"><p>The purpose of the research is to analyze current diagnostic methods for canine babesiosis and differentiate it from other blood-borne diseases.</p><sec><title>Materials and methods</title><p>Materials and methods. The study was based on long-term literature data, which was analyzed and summarized, highlighting methods for the intravital diagnosis of canine babesiosis.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Canine babesiosis is a highly prevalent, transmissible hemoprotozoan disease transmitted by ixodid ticks and found worldwide. In dogs, the primary vectors of babesiosis are ticks of the genera Rhipicephalus, Dermatocentor, and Haemaphysalis. Babesiosis is caused by single-celled protozoa of round, oval, pear-shaped, or amoeboid shapes. These organisms are transmitted by tick bites. They parasitize within red blood cells (a single red blood cell can contain from 1 to 32 individuals), blood plasma, neutrophils, and can also be found in parenchymal organs. The most common complications include hemolytic anemia, thrombocytopenia, renal and hepatic failure, and exacerbation of chronic diseases. The disease can be acute, chronic, or subclinical. The incubation period ranges from 3 to 21 days. With the subclinical form, periodic exacerbations are possible. Symptoms may depend on the severity of the disease. The most common symptoms in the acute stage include fever, lethargy, pale or icteric mucous membranes, dark urine, and anorexia. Blood tests reveal splenomegaly and hepatomegaly, and anemia, thrombocytopenia, and monocytosis are noted. Blood smear microscopy, PCR testing, and ELISA diagnostics are used to confirm the disease.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>бабезиоз</kwd><kwd>диагностика</kwd><kwd>иксодовые клещи</kwd><kwd>ПЦР</kwd><kwd>ИФА</kwd><kwd>световая микроскопия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>babesiosis</kwd><kwd>diagnostics</kwd><kwd>ixodid ticks</kwd><kwd>PCR</kwd><kwd>ELISA</kwd><kwd>light microscopy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Беломытцева Е. С., Сафиуллин Р. Т. Эффективность применения препарата Дипрокарб при бабезиозе плотоядных в Москве и Московском регионе // Российский паразитологический журнал. 2017. Т. 11. № 2. С. 183-187.</mixed-citation><mixed-citation xml:lang="en">Belomyttseva E.S., Safiullin R.T.  The effectiveness of the drug Diprocarb for babesiosis in carnivores from Moscow and the Moscow region. 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